| Avandia Makes Headlines Again: How Will the Renewed Controversy Impact the Type 2 Diabetes Drug Market?
Based on our Pharmacor advisory service entitled Type 2 Diabetes, Decision Resources is offering an exclusive analyst call entitled Avandia Makes Headlines Again: How Will the Renewed Controversy Impact the Type 2 Diabetes Drug Market? Because this presentation will feature report updates, it is ONLY available to purchasers of this Pharmacor advisory service.
Please contact us to learn how you can purchase this Pharmacor advisory service and attend the analyst call.
GlaxoSmithKline’s Avandia has been on the market for treatment of type 2 diabetes for more than a decade and in 2006, the total franchise—including Avandamet and Avandaryl—garnered nearly $2.5 billion in sales in the United States alone. However, since the 2007 publication of a controversial meta-analysis which suggested a possible increased risk of myocardial infarction associated with this drug, Avandia franchise sales have steadily declined, reaching a new low of approximately $700 million in the U.S. last year. Recently released findings from an investigation by the U.S. Senate Finance Committee have thrust Avandia under the spotlight once again, leading some to question whether the drug should be withdrawn. Furthermore, internal reports from the U.S. Food and Drug Administration (FDA) that were made public at the same time as the U.S. Senate report show disagreement within the FDA about whether Avandia should remain on the market.
Because of these differing opinions, the FDA’s Endocrinologic and Metabolic Drugs Advisory Committee will meet in July to discuss the results of Avandia’s post-marketing trials, including the RECORD trial which, as reported last year, showed no significant increase in the risk of myocardial infarction associated with Avandia. Following these recent events, Decision Resources interviewed U.S. and European thought leaders and, combined with our own analysis, insights from these interviews will be discussed in this presentation.
This 10-minute analyst call, presented by Analyst Christine Helliwell, Ph.D., will answer the following questions:
- Do key opinion leaders anticipate that Avandia will retain marketing authorization in the U.S. and Europe? Do their views coincide with Decision Resources’ own analysis?
- According to U.S. and European thought leaders, how is this latest controversy expected to impact sales of Avandia?
- How will this news affect sales of other type 2 diabetes drugs, including Takeda’s Actos, Merck’s Januvia and Lilly/Amylin’s Byetta?
- Does this controversy have potential implications for the approvability of other peroxisome-proliferator activated receptor (PPAR) agonists in development?
Dr. Helliwell will conduct a live Q & A session after the presentation.
Registration
Avandia Makes Headlines Again: How Will the Renewed Controversy Impact the Type 2 Diabetes Drug Market?
March 5, 2010 at 10 a.m. U.S. Eastern Time, 4 p.m. Central European Time (Paris).
To learn how you can purchase this Pharmacor advisory service and attend the analyst call, please contact us using the information below.
Contact Us
In North America — Keith Rourke at 781-296-2656 or krourke@dresources.com
In Europe — Kaj van Langendonck at +32-2-357-06-14 or kvanlangendonck@decisionresources.be
In Japan — Makiko Yoshimoto at +81-3-5401-2615 or makiko@dresources.jp |
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Date & Time
Friday, March 5, 2010
10 a.m. U.S. Eastern Time, 4 p.m. Central European Time Duration
10 minutes  |
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Christine Helliwell, Ph.D., is an analyst at Decision Resources. Prior to joining the company, Dr. Helliwell was an assistant editor at Genome Biology, where she was responsible for assessing manuscripts and managing the peer-review process. She holds a Ph.D. from the University of Edinburgh, where she investigated the role of epigenetic modifications in the differentiation of murine embryonic stem cells, and a B.A. from the University of Cambridge. |
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